Antifungal Lock Therapy with Liposomal Amphotericin B: A Prospective Trial.
Identifieur interne : 000145 ( Main/Exploration ); précédent : 000144; suivant : 000146Antifungal Lock Therapy with Liposomal Amphotericin B: A Prospective Trial.
Auteurs : William Mcghee ; Marian G. Michaels ; Judith M. Martin ; George V. Mazariegos ; Michael GreenSource :
- Journal of the Pediatric Infectious Diseases Society [ 2048-7207 ] ; 2016.
Descripteurs français
- KwdFr :
- Adolescent, Amphotéricine B (usage thérapeutique), Antifongiques (usage thérapeutique), Association de médicaments, Enfant, Enfant d'âge préscolaire, Femelle, Humains, Infections fongiques invasives (traitement médicamenteux), Infections sur cathéters (), Infections sur cathéters (traitement médicamenteux), Maladies intestinales (), Mâle, Nourrisson, Projets pilotes, Voies veineuses centrales (microbiologie), Études prospectives.
- MESH :
- microbiologie : Voies veineuses centrales.
- traitement médicamenteux : Infections fongiques invasives, Infections sur cathéters.
- usage thérapeutique : Amphotéricine B, Antifongiques.
- Adolescent, Association de médicaments, Enfant, Enfant d'âge préscolaire, Femelle, Humains, Infections sur cathéters, Maladies intestinales, Mâle, Nourrisson, Projets pilotes, Études prospectives.
English descriptors
- KwdEn :
- Adolescent, Amphotericin B (therapeutic use), Antifungal Agents (therapeutic use), Catheter-Related Infections (complications), Catheter-Related Infections (drug therapy), Central Venous Catheters (microbiology), Child, Child, Preschool, Drug Therapy, Combination, Female, Humans, Infant, Intestinal Diseases (complications), Invasive Fungal Infections (drug therapy), Male, Pilot Projects, Prospective Studies.
- MESH :
- chemical , therapeutic use : Amphotericin B, Antifungal Agents.
- complications : Catheter-Related Infections, Intestinal Diseases.
- drug therapy : Catheter-Related Infections, Invasive Fungal Infections.
- microbiology : Central Venous Catheters.
- Adolescent, Child, Child, Preschool, Drug Therapy, Combination, Female, Humans, Infant, Male, Pilot Projects, Prospective Studies.
Abstract
We conducted a prospective pilot study to evaluate the potential role of combined systemic antifungal and liposomal amphotericin B lock therapy in children with intestinal insufficiency with fungal catheter-related bloodstream infections whose central venous catheters had not been removed. Our results provide supportive evidence for the conduct of larger clinical trials to confirm the efficacy and safety of this approach.
DOI: 10.1093/jpids/piu083
PubMed: 26908494
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">We conducted a prospective pilot study to evaluate the potential role of combined systemic antifungal and liposomal amphotericin B lock therapy in children with intestinal insufficiency with fungal catheter-related bloodstream infections whose central venous catheters had not been removed. Our results provide supportive evidence for the conduct of larger clinical trials to confirm the efficacy and safety of this approach.</div>
</front>
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<name sortKey="Martin, Judith M" sort="Martin, Judith M" uniqKey="Martin J" first="Judith M" last="Martin">Judith M. Martin</name>
<name sortKey="Mazariegos, George V" sort="Mazariegos, George V" uniqKey="Mazariegos G" first="George V" last="Mazariegos">George V. Mazariegos</name>
<name sortKey="Mcghee, William" sort="Mcghee, William" uniqKey="Mcghee W" first="William" last="Mcghee">William Mcghee</name>
<name sortKey="Michaels, Marian G" sort="Michaels, Marian G" uniqKey="Michaels M" first="Marian G" last="Michaels">Marian G. Michaels</name>
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